Fig. 1

Schematic illustrations depicting cellular delivery of bFGF, followed by wound healing cascades of HSA-bFGF NPs. Intact bFGF has short half-life both in culture media and tissue microenvironment, thus secured crosslinking of bFGF with HSA to form a nanoparticulate is essentially advantageous for long-term supplement of biologically active bFGF in tissue regeneration