Fig. 2

Actual vs. predicted plots of responses after performing all 16 experiments and running the Standard Least Square model with emphasis on effective screening. (a) Plots for FL-cHy-NPs. (b) Plots for HK-cHy-NPs. The responses for each NP preparation are presented as ‘i’ Particle Size (nm), ‘ii’ PDI, ‘iii’ EE (%), and ‘iv’ Ld (%). In each response plot, the black dots are showing the response values obtained after performing the experiments, the blue line is representing the null hypothesis and a red slanted line as alternative hypothesis. The fainted red area around the red line representing the 95% confidence region. Here, RMSE; Root Mean Squared Error showing the average measured values of difference between the predicted and actual values. RSq (R²) values under each response plot showing how close the data fitted to the regression line (alternative hypothesis).