Fig. 4
From: Crosslinked-hybrid nanoparticle embedded in thermogel for sustained co-delivery to inner ear
Prediction profiler graphs showing optimized conditions calculated by the quadradic model using the central composite design (CCD) by JMP® pro software. The values denoted by red color showing the most optimal condition and predicted results (responses: particle size, PDI, encapsulation efficiency (EE%), and drug loading (Ld%), while the value denoted by blue color shows the range of the response values at the same synthesis conditions. The graph shows conditions for optimal synthesis of  (a) FL-cHy-NPs (b) HK-cHy-NPs.