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Table 1 Physicochemical properties of lipid nanosystems measured, after preparation, by dynamic light scattering (DLS) and laser doppler anemometry (LDA) including hydrodynamic size, polydispersity index (PdI) and zeta potential (ZP)

From: Reprogramming tumor-associated macrophages with lipid nanosystems reduces PDAC tumor burden and liver metastasis

Formulation

Mass ratio

Size (nm)

PDI

ZP (mV)

VitE:SM

1:0.1

97 ± 5

0.08 ± 0.02

– 13 ± 8

VitE:OA:SM

0.5:0.1:0.5

101 ± 3

0.21 ± 0.02

– 27 ± 1

M:SM

1:0.1

93 ± 6

0.10 ± 0.05

–10 ± 4

VitE:PC

1:0.1

125 ± 6

0.04 ± 0.01

– 5 ± 2

VitE:SM:PI

1:0.1:0.002

66 ± 3

0.20 ± 0.06

– 4 ± 2

VitE:SM:PS

1:0.1:0.002

91 ± 7

0.22 ± 0.04

– 7 ± 2

VitE:SM:PG

1:0.1:0.002

97 ± 4

0.10 ± 0.02

– 12 ± 3

VitE:SM:PA

1:0.1:0.05

100 ± 8

0.19 ± 0.03

– 12 ± 1

VitE:SM:PA002

1:0.1:0.002

95 ± 2

0.09 ± 0.02

– 10 ± 4

  1. Results are expressed as mean ± SD, n = 5. nm: nanometer, PDI polydispersity index, ZP zeta potential in millivolts (mV).