Fig. 8

The effects of ATRA-NLC-Gel on the growth and development of hair follicles in AA model mice. (A) Typical images showing hair regeneration in mice from each group after drug treatment, (n = 6). (B) Schematic illustration of the variation of hair loss area in each group with time. (C) The coverage of hair regeneration in each group at different time points, (n = 6). (D) H&E staining morphology of skin hair follicles of each group after drug administration. Scale bar: 300 μm. (E) The density of hair follicles, the thickness of the dermis (F), and the length of hair follicles (G) in mouse skin were measured by Image J software. n = 3, ^*p < 0.05, ^**p < 0.01, vs. model