Fig. 2
From: Streptococcus mutans-derived extracellular vesicles promote skin wound healing via tRNA cargo
Effect of Sm EVs on wound healing in mouse dorsal skin. (A) A 4 mm punch device was performed to create wounds on the dorsal surface of the mice, which were then randomly assigned to two groups. The experimental group received 10 µL of Sm EV solution (107 particles/mL in PBS) daily for 6 days, while the control group received 10 µL of PBS. Diagrams were created with BioRender.com. Wound areas were photographed and measured daily using a metric ruler in the images (*p < 0.05, **p < 0.01). Data are presented as the mean ± standard deviation. (B) After 6 days of treatment, the mice were sacrificed, and wound tissues were subjected to histological analysis using H&E staining. Arrows indicate the wound area.