Fig. 8

HA-ML@ES NPs regulate macrophage polarization to restore cholesterol flow homeostasis. (A) Immunofluorescence staining images of F4/80 in aortas Scale bar = 400 μm. (B) Representative images and (C) quantitative analysis of CD80 and (D) CD206 staining in aortic root sections. Scale bar = 400 μm. (E) Representative histochemistry images and (F) quantitative analysis of aortic root cross-sections stained with LOX-1 and (G) ABCG1 antibody. Scale bar = 100 μm. Date are mean ± SD (n = 3) *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001